why an vaccine for HIV/AIDS is not possible.?
explain in detail if possible.and give me information for wat is aids?and all about it till u know
Medicine - 4 Answers
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1 :
Aids is Acquired Immune Deficiency Syndrome. It starts out as HIV (Human immunodeficiency virus). There are thee stages to HIV. There are case where people have been in the HIV stages for over 10 years before AIDS took over. The person gets infected and it starts to destroy their immune system. Once it has taken a toll the immune system leaving it open to opportunistic diseases that wouldn't have the chance to infect a healthy person. Once it gets to aids it means the persons immune system has completely been destroyed. There is no vaccine because scientist haven't been able to find one yet. All their attempts have fallen through.
2 :
because it weakens ur immune system and t lymphocites which take up the vacinne
3 :
I'll answer your primar question why a vaccine has proved so difficult. HIV-1 and similar retrovirii, have a remarkable (a compliment to them, bad for us in a way) ability to change their genetic make-up. Making a vaccine means exposing an organism to the pathogen, and the organism produces antigens which then recognize the pathogen. These antigens are then harvested, purified and injected into susceptible persons. Though smallpox vaccine does not actually use smallpox virus to generate antigens, but rather a close relative variola, the method works. Not so with HIV, even if a close cousing were used, each copy of the HIV virus that is made in an infected individual millions upon millions at times, is different and would eventually conquer the protection afforded by a vaccine.
4 :
What my understanding of how vaccines work there are two main types. The first is where dead microbes are injected into a person, this then causes the bodies immune system to react and build an antibody for the microbe. Antibodies work on a simple level by making shapes which fit around the microbe, thus rendering it useless. For this to work, the antibodies in a person must be identical (and made for) the dangerous microbe which is likely to infect the person. As someone mentioned, unlike bacteria, viruses (because they are not living) have a genetic code which changes regularly. This is why a new flu vaccine is bought out each in the UK. This brings me onto the second type of vaccine. The second type is where a microbe almost identical to the dangerous one is administered to the patient, although often the bacteria or such has been genetically modified so that it is not harmful. However, the bodies immune system still reacts forms an anti-body. So how does this relate to HIV/AIDs? Well, because the viruses genetic material and "shape" is changing regularly it means most vaccines which use antibodies are deemed useless. This is the same reason viruses such as the common cold have no known cure, and although vaccines can be made by the time they are, the virus has often changed to radically for these antibodies to be effective. This doesn't however mean that there is no cure for HIV/AIDs, as it is likely with up coming nanotechnology a cure may be possible. A "vaccine" could be made by manufacturing nanobots which recognize and destroy the HIV virus. Another possible way of killing a virus is through the use of a magic bullet. Magic bullets are chemicals which can travel unnoticed through the body but have the ability to destroy microbes or bacteria. The first was discovered by Paul Ehrlich and was named Salversan 606 (or scientifically known as Arsphenamine) and had the ability to kill the syphilis microbe. So although medical science offers a possible cure for the disease in the future, it could be argued that all the money which is being invested into research for a cure the disease might be better spent buying condoms and offering education to the people in the countries suffering most heavily. Hope that answered your question, maybe a bit more thoroughly than needed but ow well, knowledge is power!
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